Try a 3rd party launcher like ADWex, Go Launcher or Launcher Pro just to name a few.
At the moment I'm using ADWex and its crazy smooth.
But 2 things first... I don't know if you do, but if you have a lot of widgets setup on your home screens they tend to eat up a lot of memory.
And second... when you use a 3rd party launcher you won't beable to use any of the stock, Sense based widgets. Like the clocks widget, contacts, calendar and so on. But on the good side there are a ton of widgets on the market to replace every one of them. And most of them are way better than anything Sense has to offer.
Decks Rom Rules, Other Roms Drool!!!
Thanks for tryin!!!