Not that it's a direct answer to your question, but many years ago (1985? 86?) as a student I did a work term for the Neil Squire Foundation (now the Neil Squire Society) in helping people with severe physical disabilities access technology. (I also did a work term at an extended care facility in Calgary.) I worked with MS patients, as well as others; we used "sip and puff" and micro-triggers, we even had one guy who could turn things off and on using his eyebrow... pretty well the only thing he still had control over. I imagine that the technology for that sort of thing has come leaps and bounds ahead of where we were at nearly 30 years ago!
Neil Squire Society
I don't know what resources your wife has access to, but the NSS specializes in that field and they may have resources (guides, videos, equipment, etc.) that can be of some service.