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First you'll want to ask yourself why you want to remove it. Bloatware is annoying, but it doesn't really slow things down. I've got enough apps that they make a small percentage of the icons in the list - and folders on home pages is a much better way to organize things anyway. And if you've managed to fill up the app space on your D2 I salute you.
Why not remove it? Because you won't get VZW OS updates if you do it wrong. Your best bet is probably Titanium Backup, it can "freeze" the bloatware apps and let you restore them for the next OTA SW upgrade. Personally I'd wait a few weeks, with any luck the D2 Gingerbread update will be coming along soon.
If you decide to go into custom ROMs and leaked software you'll be in much better shape to remove stuff.