I can't even see my device when I do "adb devices" and it was there before? When I boot it all I get is the Google name and the spinning color dots now? I know I enabled USB debugging and the device is unlocked.
This happened to me and the answer is simple just download the latest ADB and fastboot files and when you use those you will find that you will be OK. They must have had to be updated for Marshmallow.