Negative... You said you're running 4.2.2 stock, not a custom ROM, so unless you've made any significant changes to your system you should be able to update when one is released without much issue. You will probably need to reflash the stock kernel and likely recovery as well. Both of these can be pulled out of the factory image downloadable from Google and flashed in fastboot. The files in the factory image will be named recovery.img and boot.img for the recovery and kernel, respectively. You flash them in fastboot using:
fastboot flash recovery recovery.img
and
fastboot flash boot boot.img
Easy as that.