The case will not inhibit Qi charging per say, but I was unable to get my defender to fit over the Qi charging back plate once I installed it, wireless charging would still work as the plastic and rubber are not thick enough to push the phone far enough away from the charging platform.
That said, I had to choose between wireless charging and protecting my phone, I chose the later. I called OtterBox support and they have NO plans to release a version of the Defender that would allow me to use my genuine Samsung Qi charging cover. Very disappointing. response from OtterBox..
Andrew