That depends on what you're using for Sirius. I have a Sirius receiver that feeds to my FM radio, and I can run apps at the same time that the radio is running. If you're running a Sirius app, that may interfere with navigation. (A double-din radio slot, with a separator so you have 2 single-din slots makes it easier - just put a $20 radio into one of them and a single-din Android Auto in the other.)