Its running kind of funkily on my One. Any new profiles I create or edit take a long time to start working or for the changes to appear. For example, I had a profile that displayed a popup notification when I received an SMS. When I switched to Handcent I deleted that profile, but I still got the popups from Tasker for a few hours whenever Id get an SMS. It's not too terrible, but it makes testing out new profiles a huge pain.