I kept my phone in a silicone case, in a holster with a VZW anti-glare screen protector since day one. Just a few days ago I took off the screen protector and I gotta say, the screen is gorgeous. However I LOVE the way the protector felt gliding my finger across it. It was very smooth and nice. Without it it feels like if my skin is even the slightest hint of wet from humidity in the air, it gets an annoying sticky feeling, like my skin gets stuck to the screen. Very annoying. Another thing I dislike is my bloody screen got a small <1mm long scratch, extremely shallow so you can't feel it with your finger nail, but if you are out in the sunlight you WILL see it.
So I purchased a gallon of this 3M glass/paint scratch filler. Someone on this other forum said it did wonders on his Droid when he had a few scratches like mine. Gonna give it a try and post back.
Back on topic... I love the way the phone feels without a case. It has a certain texture that is grippy yet smooth to the touch. You can also feel just how thin and light this device is when its case is off. Its just a shame that while I know my screen is pretty much safe for the most part, the plastic can and will certainly get scratches/dents (I've already seen a few scratches on my silicone case that had it not been there, my phone would be permanently stuck with right now) so even though it feels amazing naked, I'll keep a case on. I might even get an Invisible Shield after I get this scratch remover liquid.