I was in the same boat... Wanted most of the aspects of N6 (large screen, front facing speakers, stock android, etc.), however, the main issue I had with it was that it was too wide for (near) comfortable 1 handed use.
The note 4 has issues as well so its not a perfect choice either. However, the pros outweigh the cons compared to the N6. And in addition, you have the SPen that adds quite a bit of functionality from a multitasking perspective that the N6 doesn't support. This became crystal clear to me yesterday when I had been out house shopping with my wife and we took several notes, pictures, and details from the various places we visited on my phone. I was able to take all of these details from the various apps I had used and saved throughout the day and combine them and send them into a single email to my wife and others interested in what we visited and saw - ALL from my Note 4. And quicker than the time it would have taken me to move/send the details to my computer to accomplish the same task (which would've been necessary had I had the N6).
Add to that it has fantastic battery life (and I can swap it out), screen is fantastic, its slimmer and feels better in the hand, its probably one of the most "useful" and "productive" mobile devices I've used since the days of win mobile on a palm treo.
My point? It depends on what you use your device for. If you're simply looking for a larger phone with front facing speakers with a near stock experience then the N6 is a fabulous device to own.
I'm using Nova Launcher that gives me that near stock experience. So the only issue that remained (like you) was the front facing speakers. IMHO if Samsung had added these to the Note 4 it'd be a near perfect device. If that's the deal breaker then the choice is made (very few phones out there have this option). Otherwise... I'd suggest trying other phones out like the note 4 or M8 to see if they are a better fit.
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