I've had tasker for years and have had a variety of actions and profiles, complex and simple but still fall back on a few core ones.
Profile: Work Times: Action to only enable the profile At Work Monday to Friday 08:00-19:00 to avoid checking when not needed
Profile: At Work: Checks for connection to the office Wifi to trigger action Vibrate Mode to put the phone on silent while at work
I also have a Pebble watch with the Glance app that contains a tasker screen.
The light goes regularly in my stair and my phone is in my shirt pocket so with both hands full of shopping I can use the watch tro turn the torch on. Also press a button to make the phone play a tone so I can find it if misplaced.
The last button speaks pre-defined text. The last time I used it some annoying kids were attempting to sing at the back of the bus just behind me. I edited the text, waited a while then pressed the button on the watch while innocently reading.
There was an announcement "Emergency! Calling the RSPCA. Cat strangulation detected."
With the phone in the top pocket I am annoyed that the screen turns on when answering or hanging up on a call that I answer via my bluetooth headset as proximity to skin through the shirt can keep the screen on and drain the battery. On the Note4 it could wipe out all my homescreen icons and input random calendar entries but the Note8 has accidental press protection that seems to mitigate this.
I use tasker to ensure the screen gets switched off on answering or hanging up on a call.