This is my first Android phone (but not my first HTC, I had a WinMo phone from them waaaaay back before the OG iPhone came out) but it seems all my hardware is rock solid, I don't see any problems with my screen or the data connection.
It's finnicky with my Ford Focus' Sync BT connection, but not with either pair of my bluetooth headsets, so I blame that more on my car than the phone.