Yes. When you want to go back to sense, just go to settings, apps, and then find Nova Launcher, select it, and press clear defaults. Then all you have to do is press the home button and a dialog will pop up. Then Just select sense and then push always.
Or another option is to just get an app such as Home Switcher. Even if you have Nova as your default launcher, you can open Home Switcher and quickly switch over to Sense, w/o having to remove Nova as your default. This allows you to easily switch back and forth. There are other apps in the store that do the same thing.