It's going to depend. If you're constantly using the device outdoors then the device is going to try to amp things up and thus battery is going to suffer. If you're indoors a lot then you'll benefit by it. I say if you are always using your phone outdoors, lower the brightness as low as you can while getting use out of the device, if that setting is higher or as high as auto-brightness, then I'd say leave auto-brightness on. Although, some people generally like the brighter screen and would prefer to just leave it on the highest setting (and then subsequently post threads about their note's poor battery performance....I know DUH right?!?!)