On a day to day function the phone does everything all my previous android phones have done, just faster. I haven't had any performance issues (runs Dungeon defenders on full settings), there was a few apps that were crashing when the phone first came out but they've been remedied. As for the screen, I can't find myself going to a smaller screen, I think it's perfect. I've also go no issues with call quality, I'd say it's average to above for a smart phone same with the speaker.
The kickstand I actually get a pretty big use out of at work, I'll prop it up and throw a video on while working for some background noise, thought the placement of the usb cable is a little annoying when trying to do this. Generally you're pretty safe with getting an HTC phone, in fact I don't think I'll be getting any other android phone.