Yeah just keep clean like any other phone and be no issues, I've open lot of times over course bof the day not sure number count but no issues there also , I use to use it like tablet but now I'm using it as a phone and tablet and love it , I've said it few times in the Forum it's my favorite device, once they make it with built in Spen that's all I'll be getting in the future.
I would be interested in a Fold if it had a built-in S Pen. I wouldn't consider one now, only because I don't want to get a huge case to keep Fold and S Pen together or put the S Pen loose in my pocket.