Unfortunately, with the current version of HTC Sense (3.0?) on this device, the Scenes profiles don't hold Lock Screen or Sound Profiles within ... so you have to manually change the lock screen if you want specific shortcuts for Home, Work, etc. E.g., out shopping during this madcap season, I like having the Clock display with LastPass (in which I store "to do" and shopping lists), Amazon Market (Search | Scan gives you a quick online price comparison, link to reviews, etc.), Wifi Analyzer, Call Log (Dialer One). But when I get home, I want the Weather display with Messages, Call Log, etc. Can't just pick a new Scene to adjust those.
"Oh bother," said Pooh.