I switched from a Tour to an Incredible. It took a couple of hours to get used to the keyboard (I ended up downloading Swype), but only real learning curve. To me, the Android platform is very intuitive.
The one thing I missed was my Outlook notes. I'm one of those weird folks who actually use them for rarely used (but sometimes needed) reference information at work. To get around this, I forwarded all of my Notes to my Gmail account and tagged them "Notes." Now I can easily access them on my DInc.
Trust me, once you make the switch you will never look back. The speed of this phone is incredible and the browser is actually usable. ;-)