Oddly timed thread topic actually.
My brother ordered a Seidio ACTIVE case the day after launch day. It just came in today. Long story short, those dolts sent him the Galaxy Note 1 ACTIVE case instead of the 2. Serious issues with this, as you'd expect. Now he has to send it back and have them send him the right one. Not cool.
But judging from the pictures of the CORRECT case for our phones, I'd say that no it should not interfere with the flash. It might block maybe a very slight amount of the left side, but for the most part given the minimum focusing distance of the camera on the Note 2, this should be insignificant at worst.