Just to help others that may run into the same issue: wiping the cache partition solved the problem I was having with the Android OS consuming most of the battery on my S6. I'm running Android 6.0.1 (Marshmallow) and recently it began losing over half the battery life in 2-3 hours. Usually, it's the screen that consumes the most battery.
I followed these instructions (which I found related to battery drain issues after upgrades), but it solved the battery drain problem I was having, even though I didn't go through a recent OS update.
Try wiping cache partition. Turn off the phone then simultaneously press on the volume UP button, the POWER button, and the HOME button until you are directed to the boot screen. Then using your volume DOWN button, select the "wipe cache partition" and press the POWER button (to execute the selected command). Then use the volume DOWN button to select YES and POWER button to confirm. Then press POWER button again and that should restart your phone.
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I followed these instructions (which I found related to battery drain issues after upgrades), but it solved the battery drain problem I was having, even though I didn't go through a recent OS update.
Try wiping cache partition. Turn off the phone then simultaneously press on the volume UP button, the POWER button, and the HOME button until you are directed to the boot screen. Then using your volume DOWN button, select the "wipe cache partition" and press the POWER button (to execute the selected command). Then use the volume DOWN button to select YES and POWER button to confirm. Then press POWER button again and that should restart your phone.
This forum ROCKS!