What is this gray box with the white circle in the center on my Note 5? How can I get rid of it?

[AC Question]

It appeared after the latest update. It moves all over the screen but will not go away.

 

[Tim1954]

Have a peek in accessibility settings for something called "assistive touch"...

 

[Kendahl Titcomb]

It appeared after the latest update. It moves all over the screen but will not go away.

Is it the s-pen in the phone because it sounds like the s-pen app