Yeah, one thing I have found is that RE-enabling apps that were disabled is problematic, about 1 out of 4 still will not work and the phone requires a Factory Reset to get things working properly again, Polaris Office is a good example of an app on the Rezound that fails to re-enable properly almost every time.
For the most part, unless you know exactly what you are disabling, only disable the VZW bloat and apps that are obviously not needed like Let's Golf and that NFL app, most Android system and HTC apps with a few exceptions shouldn't be disabled in a stock ROM.