You cant completely remove many bloat apps, but you can deactivate them. It depends on the device and carrier what you can and can not do.
For me simply disabling unused apps is sufficient. I just use application manager. Force stop, clear cache + clear data, turn off permissions, turn of notifications, restrict background data, disable. Note that disabling the app will not free up storage space, although it will prevent the app from updating and getting any bigger.
If the app has the uninstall / remove option... use that. AFIAK this will (or at least should) free up space. I have never actually verified it.
If you are unsure how important the app is, google search the name. On Verizon the go90 carrier bloat is the bad one, it installs games and other junk in the background. There may be others as well, so its good practice to kill off whatever you can.
On Verizon these are the bloat apps I deactivate. The 4-5 that I have completely un-installed don't appear on this list. You mention talkback specifically... I have not noticed any negative side effects from deleting it.