Sense ROMs have the Sense launcher, sense widgets, sense apps and all that other HTC crap. The NonSense roms don't. It definitely doesn't mean it's for advanced users though. NonSense roms are almost always faster and smoother than Sense roms. NonSense roms to me have a better feel to it. The only Sense ROM I ever used that I was able to shake off the HTC feel was Myn's. But Myn's is still slow. Which is again why i use Nonsense roms lol.