That's a tough one to answer. I've only played around with the Pre, so I don't have much experience, but much of the functionality appears to be similar between the Palm Web OS and Android. A lot of the difference comes down to how you like the implementation of the features, hardware, and small things here and there. Depending on what you're looking for in a phone, you may prefer one companies way of doing things over the other. If you're able to give both of them a shot, you may get a better idea of which phone suits your needs and your tastes. They're both capable smartphones that handle general, everyday tasks like messaging, email, and social networking without any problems and have a growing collection of apps to manage more specialized tasks. From what I've seen, the Android Market is a little more fleshed out than the Palm setup. The comparable apps seem a little smoother on Android (though that's just personal opinion and in no way fact). Really, without knowing what you're looking to do with your phone, you may be able to best get a feel for what you like with a hands on of all the options. Depending on the carrier you're with (Pre Plus has me thinking Verizon or possibly ATT), the variations in Android phones are going to greater than the standard Web OS setup.