I am using the S2 with Nexus 6P. My vehicle is a chrysler (RAM) with uconnect system. The Nexus 6p has worked flawlessly with it. First day with the watch on and connected, I answered a call and about 30 seconds into the conversation the audio dropped out (still showed phone as connected to the car), and then briefly after this, the phone disconnected completely from the car. As soon as I hung up the call, the phone would connect back to the car. If I tried to make a call again, it would disconnect the audio from the car, and then disconnect completely from the car. Since this happened the first trip after I put the watch on I figured it was the watch. Seeing this thread confirms that it is indeed the watch.