Fast boot

I am by no means an expert, just barely past newbie stage but my two cents worth is at some point in your android life you will need fastboot. Under everyday normal usage the answer is no, but when you start to have issues with performance you'll change your mind. I have in the last two weeks used it quite abit.
 
Your will encounter fewer problems with fast boot disabled. NOTE: not all apps support fast boot, and, may behave strangely, if fast boot is enabled.
 

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