You're better of than me. I graduated with BA in Illustration in 2000, went into retail, and didn't touch a pencil or brush until around 2010. I had to teach myself to paint all over again on the computer. Right now I'm just doing commissions to build up my portfolio and get my skills up to where they need to be.
None of the pieces are done completely on the Note. I only had the Note for about a year. I was only able to sketch ideas, thumbnails, color roughs, and maybe the very beginning stages of the actual illustration. I mainly used my Note to get the basic composition worked out in a couple of my latest paintings.
Theoretically I could do an illustration from start to finish solely on the Note, but it would be an uphill battle all the way.
First I find that the sensitivity as far as light pressure is not accurate. A couple of the Android apps have settings to adjust pressure, but it doesn't compare to a Wacom driver. It's not the hardware, its the software, so maybe they will fix this in time. Android painting apps are missing too many of the basic tools and features that I use regularly. I would have to switch between several apps constantly to get to the tools I need, and even then some of them just aren't available at all. It could be that I am spoiled with using Corel Painter and Photoshop on my computer. Both of those programs are packed with options.
There is no real limitation as to size with some of the apps, except PS Touch which has a limit of 3000x4000, but I have not tested the limits on the other apps. With some of the apps you can open and save as layer .psds with layers intact and would have no problem switching back and forth between your desktop and the tablet.
Its funny but PS Touch by Adobe is one of the few apps that can not open .psds with layers intact. You can only save as .psd or open a flattened .psd(layers flattened). Go figure.
There is some brush and tool switching lag when using large images on all the apps. Also the image refresh is also laggy on large images. I don't remember the limitations of the number of layers but each app was different.
I use Photoshop exclusively. I used to use Corel Painter and actually prefer it's brush engine over Photoshop, but Painter is too unstable. It crashes constantly and some of it's features don't always work the way that they are supposed to. Plus it's very heavy on system resources so you'll need a fast machine to keep it running well. I made the switch to Photoshop about 2 yrs ago but am hoping that someday Corel will be able to fix Painter. Besides the fact that Adobe has decided to go with a subscription based software, I'm very happy with only using Photoshop CS6. It has all the tools I need in one package.
With my workflow I use the transform/warp tool a lot, as well as cut, copy and paste. It helps to quickly move and resize elements of the painting around to get the best composition. I also need to be able to adjust color, saturation, and brightness/contrast, of a particular selection or layer. I also use a lot of photo textures so I need different blending modes for the layers. For me there is no Android app that does all of these functions, and some are functions not available at all. So it would take me a lot longer to make changes that would normally be quick.
If line work is especially important to you style, Sketchbook Pro is probably your best bet on Android. I think it has the best brush responsiveness by far. LayerPaint HD has the best UI(similar to Paint Tool Sai). PS Touch is the only app which you can adjust(color, brightness, etc.) of a particular selection or layer. All the other apps can adjust only the entire image. Clover Paint has got potential but the UI is too much of pain to set up.
Having said all that, I think the Note 10.1 is the one of best tablets with a mobile operating system(android,iOS, windows RT)for drawing.
Forgot to mention that any tablet using a Wacom digitizer can also use some of the older Wacom pens. Here is a link to which pens can be used (only the ones in the first grouping can be used)
Wacom Asia Pacific | Pen Compatibility