Well, I have the 4.2.2 update on now but not enough time has lapsed to figure it out.
Part of the issue I was encountering (I think) was also being influenced by something else. I keep my phone in my pants pocket, screen facing inward. It was stored in only one of two conditions: between my body and my wallet for extra protection, or just in the pocket without my wallet on top of it. Nothing whatsoever special about the wallet.
Anyhow, I would sometimes find the phone was turned back on (screen turned on) when it was in my pocket, even though I can be absolutely certain the power button itself was NEVER touched by anything. So, for whatever reason, it would come on. Then, it would start going through different things (clock widget, maybe some app on the home screen, maybe the app launcher, maybe settings) and I'm thinking that it kept being forced effectively to change settings or just have various unintended activities performed on it. In fact, on one occasion, the phone had gotten uncomfortably hot and when I yanked it out of my pocket, it had already locked up by that point, and so I had to force-cycle it.
Anyhow, I now store my phone differently, and so that issue no longer takes place.
Again, if I see any real results or anything worth reporting, I'll mention it either here or in some other appropriate thread.