My JDS Labs ODAC works with my Verizon S8 without changing any settings. Just plugs in and works. This isn't something I'm going to ever use, but I did test it, and it does work.
The phone itself, a Verizon Snapdragon S8, works fine in my opinion with normal easy to power headphones like most in ear monitors, and low impedance, somewhat sensitive over the ear models like the ATH-M50x, and Brainwavz HM5. Harder to drive headphones like a Sennheiser HD650, or AKG Q701 deserve more power.
My last phone was an LG V10 that has ESS Sabre DAC and amplifier chips inside. The S8 doesn't have the same kind of power, but in terms of actual sound quality the S8 is 95% as good. What I do like is the system wide EQ that the S8 offers. With a small amount of EQ I can actually stand to listen to the supplied AKG earphones and my ATH-M50x. I find that most headphones either has a little too much bass, or need a small bass boost. It's very hard for me to find anything with the exact balance I prefer. So this is a big help. My HD650 with my desktop amp and DAC is just about perfect, but for on the go the S8 is just fine with me.