I don't think the lack of removable battery and no SD card slot will be an issue for most. And with the multiple awesome charging options, hopefully the smaller battery size wont be as much as an issue as it seems.
Yes, please! Would love to try out the new S Pen and Touchwiz. I have only had Moto phones, so would be interesting to see what the big deal is with the most popular phone manufacturer's UI.
Looking forward on having my first Galaxy Note and play a lot wth that S-Pen, that camera, and the ability to take a quick note with the screen off looks quite nice