I have a scheme that works pretty well for me (I originally saw it as a suggestion for the iPhone).
What I do is I treat each row in my app drawer as a folder. The first three items in that row are the top 3 most used apps that would be in that folder, and the last item is the folder itself. I've attached a screenshot to help explain.
My first page, for example, has my "media" applications. The first row is Audio, the next is Video, the third is Picture, and the fourth is Text. I just happen to have enough apps that fall into each of those categories for that separation to make sense for me. You might prefer something different.
I like this method because I don't have to read the label of a folder to know what apps it has. I also try to keep my pages separated by generally similar categories.
Page 1 is Media, Page 2 is Games, Page 3 are utility type things, etc. This method requires a little bit of upkeep when you download new apps, or if you beat a game and want to switch it out of your top 3, but I find it's convenient enough 95% of the time to make it worth it to me. (It also is fairly easy for somebody else to figure out where something might be).