Why did my home screen buttons randomly become unresponsive?

[Android Central Question]

Recently I started having issues with the app "buttons" on my home screen becoming unresponsive. The all apps button still works, but when I trap any other app it moves like I've hit it, but does nothing. Only solution I have found is restarting the phone.

 

[B. Diddy]

Welcome to Android Central! Which phone? Does it persist in Safe Mode? Or are you in Easy Mode?