The placement of the antennas is problematic. It is impossible NOT to block all of them, just by holding it In a natural position. Coupled with weak radios, that could explain why the nexus is slower. (I've noticed speed tests are significantly faster when the device is not being held)
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What? The Galaxy Nexus has its CDMA radio in the lower-left hand corner of the device (when looking at the screen), the Bluetooth/Wifi antenna on the center right, and the LTE radio on the top left. It's impossible to block all of these antennas unless you're death gripping your phone with both hands, in which case you would just look stupid. Unless you're holding your phone in landscape mode (either clockwise or counterclockwise), you'll never even touch the LTE radio unless you have the hands of a giant. I have big hands and mine still don't come anywhere near it. Additionally, unless you're left handed, you probably won't cover the CDMA antenna well enough to cause any sort of signal problems.
edit: Source for the Galaxy Nexus, complete with diagram: http://www.engadget.com/2011/11/15/samsung-galaxy-nexus-nabs-fcc-approval-complete-with-verizon-lte/
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