Had same problem - my Samsung Note could not read my external SDcard at all.
Error: "SD card blank or or has unsupported filesystem"
If you use an Apple Mac OS X for backup or just even open or syncing than OSX writes certain
files onto your SD card and Android can't read these files.
My solution:
Insert your SDcard into an adapter and connect to your PC/Mac and open the SDcard.
I deleted these OS X files:
.Spotlight-V100
.Trashes
._.Trashes
.disk
.fseventsd
Thereafter all apps opened again on my Galaxy Note and I could read all files again.