I have so say my only 2 dislikes about this phone so far is that:
NFC payments get spotty on when they work when using other NFC apps (I used a credit card reader app to show someone how easy it can be to take some simple credit card info from an NFC capable credit card. I used my own card, my phone isn't rooted) and it seemed like NFC payments were dead after that until I rebooted. Worked fine after a reboot.
And
The AMOLED screen. It's a great screen, but I still every once in a while feel the pit in my stomach that at some point it'll degrade and I'll start seeing burn in. Nothing yet, and maybe it won't in the time I have this phone, but I guess I'll feel that way about any OLED screened device I own.
Otherwise, I cannot praise this phone enough for how absolutely beast mode it is with everything else I throw at it. I'm particularly fond of the relationship I have created with it and my Nexus player and Chromecast. Pure Google alllll the way. And my Bluetooth has been stellar. I have a Bluetooth audio aux dongle in my car and have never had a pairing issue. Super convenient. My Bluetooth headset never fails me, my Garmin vivosmart works like a champ, and my bluetooth profiles in the company cars pick it right up and hold it when I take them for a drive out on a work errand. Truly sorry for those that do have issues, but I'd go out on a limb and say its probably the other device causing the issues, not your nexus.
I do have to say that if this phone was any bigger, and I mean ANY bigger, it would probably not have worked for me. It still teeters on the line of practicality for some of my interests, and if this were the same size or bigger than the nexus 6 from last year I think it would be too much. That's not to say I don't enjoy having the screen real estate though, TV shows in bed have never been better!