Well, I have Chrome as the browser. Are there any settings within the Chrome Android app that I need to tweak? But I don't suspect such a popular browser would pose an issue. Right?Are you using any security or antivirus apps?
Another thing we didn't discuss was if you tried a different browser.
Typically, to get out of Safe Mode, all you have to do is reboot. A reboot without using the Safe Mode keypress combination should get you back into normal mode. Safe Mode technically shouldn't mess up any apps, but if it does, that may have to do more with deficiencies in how those apps are coded (or perhaps with how the phone's firmware is coded).