I've had the clear vskin for a couple days and I think the buttons are very responsive on mine. In fact, so much so that I only have to press about 1/2 as hard as usual for them to work, kinda nice.
The PROBLEM for me with the case is that they put their honking logo on the back right over top of where my personal engraving or whatever you want to call it resides on the phone so it is no longer legible/viewable. I realize it's not the end of the world, but for this phone and the customization that is part of what makes it so great, this is a very poor oversight on manufacturers part.
The case is slim, will def help with scratches and maybe small drops but is in no way something that I think will help much in a sizeable drop of any kind, which is OK by me.
I am hoping the CaseMate naked tough case clear comes back in stock soon.