I just moved up to a N2 from a Thunderbolt, and it is better in so many ways, some expected, some not expected. I had screen on time of 4 hours yesterday, LTE the whole day, after 14 hours my battery was at 47%. With my Thunderbolt, I would have needed to put it on the charger by 4pm. I'm still getting used to *not* having to look at battery stats all day and micromanaging brightness, LTE, etc. (The main difference seems to be that with LTE on and the screen off, the phone is very, very efficient and hardly loses battery at all, maybe 1%/hour, not the 10%/hour that I was seeing with the T-bolt, screen off, LTE on. The screen uses about 11%/hour, which is why we are seeing screen on times in the 7-8 hour range. Awesome.)
The GPS locks on much, much faster; the boot up time is about 1 minute vs. 5 (not that I need to reboot anymore, as I did several times daily with the TB), the battery meter is much more accurate, the regular multitasking (not multiwindow) works much better with 2GB RAM instead of 0.75GB (and Sense bloat). Typing is also a lot more accurate. There is a notification light, and push mail works much better and more consistently. All that is beyond the obvious upgrades of screen size and much faster (4-5x as fast) processor, which makes a big difference when opening/resizing web pages, opening/moving around in PDFs, etc (I don't play any processor-intensive games, so can't comment on that).
On the minus side, it's a little heavier, harder to manage with one hand, somewhat less comfortable to hold (in size and texture), harder to get out of the pants, and I have a nagging worry about dropping it, after seeing that poor guy's N2 with a cracked screen after one day.
This is a tremendous improvement over the Tbolt!